# Bioavailability and Lag

[Generated automatically as a Tutorial summary]

## Inputs

### Description

Name: | biolag_abs_bio
Title: | Bioavailability and Lag
Author: | Wright Dose Ltd
Abstract: |

One compartment model absorption dosing with bioavailability and lag parameters.

Keywords: | identifiability; bioavailability; lag
Input Script: | `biolag_abs_bio_tut.pyml`
Diagram: |

### True f[X] values

    f[KA] = 0.3000
    f[CL] = 3.0000
    f[V] = 20.0000
    f[ANOISE_STD] = 1.0000
    f[BIO] = 0.5830
    f[LAG] = 0.0000

### Starting f[X] values

    f[KA] = 0.5000
    f[CL] = 1.0000
    f[V] = 15.0000
    f[ANOISE_STD] = 5.0000
    f[BIO] = 0.8000
    f[LAG] = 1.0000

## Outputs

### Generated data .csv file

Synthetic Data: | `synthetic_data.csv`

### Generating and Fitting Summaries

- Gen: Bioavailability and Lag (gen)
- Fit: Bioavailability and Lag (fit)

### Fitted f[X] values

    f[KA] = 1.0000
    f[CL] = 2.1152
    f[V] = 8.3532
    f[ANOISE_STD] = 0.8936
    f[BIO] = 0.2407
    f[LAG] = 9.2028

## Plots

### Dense comp plots

Alternatively see All dense_comp graph plots

## Comparison

### True objective value

    44.2050

### Final fitted objective value

    38.7412

### Compare Main f[X]

Name | Initial | Fitted | True | Prop. Error | Abs. Error
--- | --- | --- | --- | --- | ---
f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01
f[CL] | 1 | 2.12 | 3 | 29.49% | 8.85e-01
f[V] | 15 | 8.35 | 20 | 58.23% | 1.16e+01
f[BIO] | 0.8 | 0.241 | 0.583 | 58.71% | 3.42e-01
f[LAG] | 1 | 9.2 | 0 | inf | 9.20e+00

### Compare Noise f[X]

Name | Initial | Fitted | True | Prop. Error | Abs. Error
--- | --- | --- | --- | --- | ---
f[ANOISE_STD] | 5 | 0.894 | 1 | 10.64% | 1.06e-01

### Compare Variance f[X]

No Variance f[X] values to compare.