# One Compartment Model with Absorption and Inter-subject Variance f[CL_isv]=0.2

[Generated automatically as a Fitting summary]

## Inputs

### Description

Name: | d1cmp_cl_isv
Title: | One Compartment Model with Absorption and Inter-subject Variance f[CL_isv]=0.2
Author: | Wright Dose Ltd
Abstract: |

Population one Compartment Model with Absorption and Inter-subject Variance

Keywords: | one compartment model; dep_one_cmp_cl
Input Script: | `d1cmp_cl_isv_fit.pyml`
Input Data: | `synthetic_data.csv`
Diagram: |

### Initial fixed effect estimates

    f[KA] = 0.5000
    f[CL] = 1.0000
    f[V] = 15.0000
    f[PNOISE_STD] = 0.2000
    f[ANOISE_STD] = 0.2000
    f[CL_isv] = 0.0100

## Outputs

### Final objective value

    -394.5900

which required 1.22 iterations and took 467.27 seconds

### Final fitted fixed effects

    f[KA] = 0.3020
    f[CL] = 3.2966
    f[V] = 19.6506
    f[PNOISE_STD] = 0.0712
    f[ANOISE_STD] = 0.0545
    f[CL_isv] = 0.1844

### Fitted parameter .csv files

Fixed Effects: | `fx_params.csv (fit)`
Random Effects: | `rx_params.csv (fit)`
Model params: | `mx_params.csv (fit)`
State values: | `sx_params.csv (fit)`
Predictions: | `px_params.csv (fit)`

## Plots

### Dense sim plots

Alternatively see All dense_sim graph plots

## Comparison

### Compare Main f[X]

Variable Name | Starting Value | Fitted Value | Prop Change | Abs Change
--- | --- | --- | --- | ---
f[KA] | 0.5000 | 0.3020 | 0.3961 | 0.1980
f[CL] | 1.0000 | 3.2966 | 2.2966 | 2.2966
f[V] | 15.0000 | 19.6506 | 0.3100 | 4.6506

### Compare Noise f[X]

Variable Name | Starting Value | Fitted Value | Prop Change | Abs Change
--- | --- | --- | --- | ---
f[PNOISE_STD] | 0.2000 | 0.0712 | 0.6439 | 0.1288
f[ANOISE_STD] | 0.2000 | 0.0545 | 0.7276 | 0.1455

### Compare Variance f[X]

Variable Name | Starting Value | Fitted Value | Prop Change | Abs Change
--- | --- | --- | --- | ---
f[CL_isv] | 0.0100 | 0.1844 | 17.4397 | 0.1744