# One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5

[Generated automatically as a Tutorial summary]

## Inputs

### Description

Name: | dep_one_cmp_cl_iov_05
Title: | One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5
Author: | Wright Dose Ltd
Abstract: |

Population one Compartment Model with Absorption and Inter-occasion Variance
Here f[CL_isv] true value is 0.5

Keywords: | one compartment model; dep_one_cmp_cl; iov
Input Script: | `dep_one_cmp_cl_iov_05.pyml`
Diagram: |

Failed to create compartment diagram

### True f[X] values

    f[KA] = 0.3
    f[CL] = 3
    f[V] = 20
    f[PNOISE_STD] = 0.1
    f[ANOISE_STD] = 0.05
    f[CL_isv] = 0.5
    f[CL_iov] = 0.01

### Starting f[X] values

    f[KA] = 0.5
    f[CL] = 1
    f[V] = 15
    f[PNOISE_STD] = 0.2
    f[ANOISE_STD] = 0.2
    f[CL_isv] = 0.01
    f[CL_iov] = 0.01

## Outputs

### Generating and Fitting Summaries

- Gen: One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5 (gen)
- Fit: One Compartment Model with Absorption and Inter-occasion Variance f[CL_isv]=0.5 (fit)

### Fitted f[X] values

    f[KA] = 1
    f[CL] = 1.8513
    f[V] = 20.269
    f[PNOISE_STD] = 0.21367
    f[ANOISE_STD] = 0.047704
    f[CL_isv] = 0.26995
    f[CL_iov] = 0.0085567

## Plots

### Dense comp plots

Alternatively see All dense_comp graph plots

## Comparison

### True objective value

    -352.854755698

### Final fitted objective value

    -276.581051572

### Compare Main f[X]

Name | Initial | Fitted | True | Prop. Error | Abs. Error
--- | --- | --- | --- | --- | ---
f[KA] | 0.5 | 1 | 0.3 | 233.33% | 7.00e-01
f[CL] | 1 | 1.85 | 3 | 38.29% | 1.15e+00
f[V] | 15 | 20.3 | 20 | 1.35% | 2.69e-01

### Compare Noise f[X]

Name | Initial | Fitted | True | Prop. Error | Abs. Error
--- | --- | --- | --- | --- | ---
f[PNOISE_STD] | 0.2 | 0.214 | 0.1 | 113.67% | 1.14e-01
f[ANOISE_STD] | 0.2 | 0.0477 | 0.05 | 4.59% | 2.30e-03

### Compare Variance f[X]

Name | Initial | Fitted | True | Prop. Error | Abs. Error
--- | --- | --- | --- | --- | ---
f[CL_isv] | 0.01 | 0.27 | 0.5 | 46.01% | 2.30e-01
f[CL_iov] | 0.01 | 0.00856 | 0.01 | 14.43% | 1.44e-03